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Alcohol Use Disorders: Diagnosis and Clinical Management of Alcohol-Related Physical Complications [Internet]

Alcohol Use Disorders: Diagnosis and Clinical Management of Alcohol-Related Physical Complications [Internet]

NICE Clinical Guidelines - National Clinical Guideline Centre (UK)

Version: 2010

Evidence Tables

Unclear allocation concealment

Alcohol-related Pancreatitis

Prolonged hazardous drinking can result in progressive and irreversible damage to the pancreas gland. This occurs on the background of pancreatic inflammation, acinar atrophy and, ultimately, fibrosis and can result in significant exocrine and endocrine insufficiency. Some individuals may develop this condition with alcohol intakes as low as 20 g/day; others may need to drink in excess of 200 g/day before evidence of the disease develops; others may never develop this condition no matter how much they drink or for how long. In susceptible individuals the longer the duration of drinking the greater the risk of developing significant pathology.

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