Appendix Table 1Diagnostic hiearchy and ICD-9-CM diagnosis and procedure codes

Rank in HierarchyDescriptionICD-9-CM Codes (PR for procedure codes) Coding based on the presence of any eligible code within a hospitalization
1Hemophilia A and B286.0, 286.1
2Hemophilia-related off-label286.2, 286.3, 286.4, 286.5, 287.1, 287.3, 287.9
3Brain trauma852, 853
4Body traumaAll E-codes except E85, E87, E92, E93, E94; PR 81–90, 92–95, 98
5Intracranial hemorrhage430, 431, 432
6Brain surgeryPR 1
7Pediatric cardiac surgeryPR 35, 36, 37 (except 37.2) and age <18
8Adult cardiac surgeryPR 35, 36, 37 (except 37.2) and age ≥18
9Obstetrics72, 73, 74, 75; PR 63, 64, 65, 66, 67 (except 67.8)
10Neonatal conditionsV3, 76, 77 (except for 76.0, 76.1, 76.2, 76.3) and age < 1 year
11Aortic aneurysm441
12ProstatectomyPR 60
13Other vascular surgeryPR 39 (except 39.94, 39.95, 39.96)
14Liver transplantationPR 50.5
15Liver biopsyPR 50.1, 50.2
16Esophageal varices456.0, 456.1, 456.2
17Other liver disease571, 572
18Other gastrointestinal bleed530.4, 531–535, 537, 557, 562, 569, 578
19Other secondary hematological conditions287 (except 287.1, 287.3, 287.9), 446.6, 283.1, 286.6, 286.7, 286.9, 964.2, V58.61, V58.63, E585.2, E934.2
20Pulmonary disease786.3, 770.3; PR 32, 33, 34
21Cancer140–230
22Other surgical proceduresPR ≤87 (except 39.8)
23Other, without proceduresAll remaining codes

From: Appendix C, Additional Analyses, Tables, and Figures

Cover of Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care
Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care [Internet].
Comparative Effectiveness Reviews, No. 21.
Yank V, Tuohy CV, Logan AC, et al.

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