TABLE 27Weight gain in children with persistent diarrhoea

StudyTreatment armsp-value
Amadi et al. 2005,52, Amadi et al. 200258Neocate     Standard skimmed milk/soy-based diet
Median weight gain (IQR), kgn = 79     n = 78
 From admission1.10 (0.55–1.55)     0.75 (0.2–1.3)0.006
 From nadir1.7 (1.2–2.0)     1.2 (0.6–1.7)0.002
Bhutta et al. 199453Soy (n = 21)     KY milk (n = 19)
Mean weight change ± SD, g/kg/daya
 Week 17.1 ± 11.3     3.1 ± 12.1NS
 Week 211.6 ± 10.0     4.3 ± 7.2< 0.02
Mean weight change ± SD, g/kg/day3.7 ± 5.9     7.9 ± 9.7NS
Percentage (n/N) of participants who lost weight10 (2/21)     37 (7/19)NS
Nurko et al. 199756Chicken (n = 15)Nursoy (n = 13)Vivonex (n = 13)
Mean weight ± SD, g
 At admission3572 ± 8233270 ± 11673764 ± 1575NR
 At end of protocol3736 ± 870b3495 ± 1172b3940 ± 1599b
 At time of discharge4133 ± 1160c3797 ± 1128c4225 ± 1706c

NR, not reported; NS, not statistically significant.

a

Not explicitly stated, but data presumed to be mean ± SD.

b

p < 0.05 admission vs end of protocol.

c

p < 0.05 admission vs discharge.

From: 4, Assessment of clinical effectiveness

Cover of The Effectiveness of Interventions to Treat Severe Acute Malnutrition in Young Children: A Systematic Review
The Effectiveness of Interventions to Treat Severe Acute Malnutrition in Young Children: A Systematic Review.
Health Technology Assessment, No. 16.19.
Picot J, Hartwell D, Harris P, et al.
Southampton (UK): NIHR Journals Library; 2012 Apr.
© 2012, Crown Copyright.

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