Table 27Suggested site-specific investigations in the diagnosis and assessment of non-respiratory TB

SiteImagingBiopsyCulture
Lymph node
  • Node
  • Node or aspirate
Bone/joint
  • Plain X-ray and computed tomography (CT)
  • Magnetic resonance imaging (MRI)
  • Site of disease
  • Biopsy or para-spinal abscess
  • Site or joint fluid
Gastrointestinal
  • Ultrasound
  • CT abdomen
  • Omentum
  • Bowel
  • Biopsy
  • Ascites
Genitourinary
  • Intravenous urography
  • Ultrasound
  • Site of disease
  • Early morning urine
  • Site of disease
  • Endometrial curettings
Disseminated
  • High resolution CT thorax
  • Ultrasound abdomen
  • Lung
  • Liver
  • Bone marrow
  • Bronchial wash
  • Liver
  • Bone marrow
  • Blood
Central nervous system
  • CT brain
  • MRI
  • Tuberculoma
  • Cerebrospinal fluid (CSF)
Skin
  • Site of disease
  • Site of disease
Pericardium
  • Echocardiogram
  • Pericardium
  • Pericardial fluid
Cold/liver abscess
  • Ultrasound
  • Site of disease
  • Site of disease

From: 5, Diagnosis

Cover of Tuberculosis
Tuberculosis: Clinical Diagnosis and Management of Tuberculosis, and Measures for Its Prevention and Control.
NICE Clinical Guidelines, No. 117.
National Collaborating Centre for Chronic Conditions (UK); Centre for Clinical Practice at NICE (UK).
Section 5.1, Copyright © 2011, National Institute for Health and Clinical Excellence. Sections 5.2 to 5.4, Copyright © 2006, Royal College of Physicians of London.

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