Table A-2Search strategy for observational studies (February 2012)

StepCategoryTermsResults
1Newer anticoagulantsDabigatran[tiab] OR desirudin[tiab] OR edoxaban[tiab] OR rivaroxaban[tiab] OR apixaban[tiab] OR betrixaban[tiab] OR YM150[tiab] OR razaxaban[tiab] OR “dabigatran etexilate”[Supplementary Concept] OR “desirudin”[Supplementary Concept] OR “edoxaban”[Supplementary Concept] OR “rivaroxaban”[Supplementary Concept] OR “apixaban”[Supplementary Concept] OR “betrixaban”[Supplementary Concept] OR “razaxaban hydrochloride”[Supplementary Concept] OR “factor Xa, Glu-Gly-Arg-”[Supplementary Concept] OR “KFA1411”[Supplementary Concept] AND1112
2Disorders of interest“Venous Thrombosis”[Mesh:noexp] OR “Venous Thromboembolism”[Mesh] OR “Pulmonary Embolism”[Mesh] OR “Atrial Fibrillation”[Mesh] OR “Heart Valve Prosthesis”[Mesh] OR “Aortic Valve”[Mesh] OR “Mitral Valve”[Mesh] OR “deep vein thrombosis”[tiab] OR “atrial fibrillation”[tiab] OR dvt[tiab] OR “pulmonary embolism”[tiab] OR “mechanical heart valve”[tiab] OR “mechanical heart valves”[tiab] OR “mechanical valve”[tiab] OR “mechanical valves”[tiab] OR “mechanical aortic”[tiab] OR thromboembolism[tiab] AND145374
3Study designs(“evaluation studies”[Publication Type] OR “evaluation studies as topic”[MeSH Terms] OR “evaluation study”[tiab] OR evaluation studies[tiab] OR “intervention studies”[MeSH Terms] OR “intervention study”[tiab] OR “intervention studies”[tiab] OR “case-control studies”[MeSH Terms] OR “case-control”[tiab] OR “cohort studies”[MeSH Terms] OR cohort[tiab] OR “longitudinal studies”[MeSH Terms] OR “longitudinal”[tiab] OR longitudinally[tiab] OR “prospective”[tiab] OR prospectively[tiab] OR “retrospective studies”[MeSH Terms] OR “retrospective”[tiab] OR “follow up”[tiab] OR “comparative study”[Publication Type] OR “comparative study”[tiab] OR “Case Reports”[Publication Type] OR “case report”[tiab] OR “case series”[tiab] OR observational[tiab]) NOT (Editorial[ptyp] OR Letter[ptyp] OR Comment[ptyp])4927238
3Combine results and apply limits#1 AND #2 AND #3
Publication Date from 2001 to 2012
278
4Additional study designs“Case Reports”[Publication Type] OR “Case-Control Studies”[Mesh]) OR “Cohort Studies”[Mesh] OR “case report”[tiab] OR cohort[tiab] OR case- control[tiab] OR “case series”[tiab]2841521
5Combine results and apply limits#1 AND #2 AND #4 Publication Date from 2001 to 201247

From: APPENDIX A, SEARCH STRATEGIES

Cover of Comparative Effectiveness of Warfarin and Newer Oral Anticoagulants for the Long-Term Prevention and Treatment of Arterial and Venous Thromboembolism
Comparative Effectiveness of Warfarin and Newer Oral Anticoagulants for the Long-Term Prevention and Treatment of Arterial and Venous Thromboembolism [Internet].
Adam SS, McDuffie JR, Ortel TL, et al.
Washington (DC): Department of Veterans Affairs (US); 2012 Apr.

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