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List of abbreviations

All abbreviations that have been used in this report are listed here unless the abbreviation is well known (e.g. NHS), or it has been used only once, or it is a non-standard abbreviation used only in figures/tables/appendices, in which case the abbreviation is defined in the figure legend or in the notes at the end of the table.

Background

Breast cancer is the uncontrolled, abnormal growth of malignant breast tissue affecting predominantly women. Though frequently referred to as a homogeneous disease, breast cancer has been recognised as a biologically heterogeneous disease with several subgroups, including those with different stages and types of the disease. Metastatic breast cancer (mBC) is an advanced stage of the disease when the disease has spread beyond the original organ. Common sites of metastasis include bone, the liver, lung and brain.

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