This figure shows the effect size for each study in a forest plot for all combined therapy vs combined therapy studies for the outcome of response. All studies show a relative risk that crosses 1 (no difference) between groups.

Figure 12Forest plots of the combined versus combined therapies for the outcome of response

BUP = bupropion; BUS = buspirone; CBT = cognitive behavioral therapy; CIT = citalopram; CM = clomipramine; Med = medication; DES = desipramine; FLX = fluoxetine; H = Hamilton Depression Rating Scale; H-17 = Hamilton Depression Rating Scale – 17 item; H-21 = Hamilton Depression Rating Scale – 21 item; LI = lithium; M = Montgomery-Asberg Depression Rating Scale (MADRS); Q-16 = Quick Inventory of Depressive Symptoms Self Report (16); SER = sertraline; SSRI = selective serotonin reuptake inhibitors

* Represent STAR*D studies.

From: Results

Cover of Treatment for Depression After Unsatisfactory Response to SSRIs
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Santaguida PL, MacQueen G, Keshavarz H, et al.

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