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Drug Therapy for Rheumatoid Arthritis in Adults: An Update [Internet]

Drug Therapy for Rheumatoid Arthritis in Adults: An Update [Internet]

Comparative Effectiveness Reviews - Agency for Healthcare Research and Quality (US)

Version: April 2012

Results

Figure 1 depicts the disposition of identified articles. We included 258 published articles reporting on 211 studies: 31 head-to-head randomized controlled trials (RCTs), 1 head-to-head nonrandomized controlled trial, 44 placebo-controlled trials, 28 meta-analyses or systematic reviews, and 107 observational studies. Our findings include studies rated good or fair for internal validity, unless a particular study rated poor provides some unique information that we judged to be of interest. Most studies were of fair quality; we designate in the text only those of good or poor quality. Evidence tables for included studies, by Key Question (KQ), can be found in Appendix E.

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