Table 2Pharmaceutical treatments for rheumatoid arthritis: Corticosteroids

Generic NameManufacturer
U.S. Trade Name(s)*
How SuppliedUsual Adult Dose
Cortico-steroids:
Methyl-prednisolone
Multiple
Medrol®, Depo-Medrol®, Solu-Medrol®
Acetate - Injectable
IM—20, 40, and 80 mg/ml

Sodium succinate - Injectable:
IM—40, 125, and 500 mg, 1 and 2 g vials

Oral:
Tabs—2, 4, 8, 16, and 32 mg
Acetate:
IM—10 to 80 mg every 1 to 2 weeks
Intra-articular, intralesional —4 to 80 mg every 1 to 5 weeks

Sodium succinate:
IM—10 to 80 mg daily
IV—10 to 40 mg every 4 to 6 hours; up to 30 mg/kg every 4 to 6 hours

Oral:
2 to 60 mg in 1 to 4 divided doses to start, followed by gradual reduction
PrednisoneMultiple
Deltasone®, Sterapred®, LiquiPred
Oral Solution—1 and 5 mg/ml
Tabs—1, 2.5, 5, 10, 20, and 50 mg
Use lowest effective dose. Usually ≤ 10 mg/day, but doses range from 5–60 mg/day
PrednisoloneMultiple
Orapred®, Pediapred®, Prelone®, Delta-Cortef®, Econopred®
Oral Solution/Syrup—5, 15, and 20 mg/5 ml
Oral Tabs—5 and 15 mg
Use lowest effective dose (5 to 7.5 mg/day), up to 60 mg/day

IM = intramuscular; IV = intravenous; kg = killigram; mg = milligram; ml = millileter

*

Listed trade names are limited to commonly prescribed U.S. products w hen multiple trade names are available.

From: Introduction

Cover of Drug Therapy for Rheumatoid Arthritis in Adults: An Update
Drug Therapy for Rheumatoid Arthritis in Adults: An Update [Internet].
Comparative Effectiveness Reviews, No. 55.
Donahue KE, Jonas DE, Hansen RA, et al.

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