Abstract Review Questions

Original research (no review articles, editorials, letters to the editor) published in English after 1990 in adult patients with rheumatoid or psoriatic arthritis AND is not a case report or case series?Yes
No
Cannot determine
No, but article will be used for background
Study includes one or more of the following pharmaceutical interventions (check all that apply):Corticosteroids
Oral DMARDs including methotrexate, leflunomide, sulfasalazine, cyclosporine, hydroxychloroquine
Biologic DMARDs including anakinra, etanercept, infliximab, adalimumab, abatacept, certolizumab, golimumab, tocilizumab, rituximab
Cannot determine
Comparison is not of interest
Study compares:Two of the included drugs
Biological DMARD (TIM) versus placebo
One of the included drugs versus placebo but is of interest because of specific outcomes such as adverse events
Nothing of interest and article should not be included
Cannot determine
Addresses one or more of the following key questions (check all that apply):KQ1 For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in their ability to reduce patient-reported symptoms, to slow or limit progression of radiographic joint damage, or to maintain remission (reduce the incidence flareups?
KQ2- For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in their ability to improve functional capacity or quality of life?
KQ3 For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in harms, tolerability, adherence, or adverse effects?
KQ4 What are the comparative benefits and harms of drug therapies for rheumatoid arthritis and psoriatic arthritis in subgroups of patients based on stage of disease, history of prior therapy, demographics, concomitant therapies, or comorbidities?
Cannot determine by the title or abstract
None of the above
Study design is one of the following:RCT 3 months or longer
Meta-analysis or systematic review
Observational Study (N is greater or equal to 100) 3 months or longer
Case series
Case report
None of the above – so exclude
None of the above – but include
Cannot determine

From: Appendix B, Review and Abstraction Forms

Cover of Drug Therapy for Rheumatoid Arthritis in Adults: An Update
Drug Therapy for Rheumatoid Arthritis in Adults: An Update [Internet].
Comparative Effectiveness Reviews, No. 55.
Donahue KE, Jonas DE, Hansen RA, et al.

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