Table 95Results of univariate meta-regression in naltrexone versus placebo trials

Variablesk (n)Coefficient (standard error)95% CIAdjusted Pa
Baseline drinking20 (3338)−0.003 (0.002)−0.007 to −0.0010.04
Constant−0.19 (0.16)−0.15 to 0.530.25

Note. k = number of studies; n = number of participants.


Calculated using the Higgins and Thompson Monte Carlo permutation test (10,000 permutations).


Cover of Alcohol-Use Disorders
Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence.
NICE Clinical Guidelines, No. 115.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2011.
Copyright © 2011, The British Psychological Society & The Royal College of Psychiatrists.

All rights reserved. No part of this book may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers. Enquiries in this regard should be directed to the British Psychological Society.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.