Table 108Summary of the data reported in the RCTs included in the guideline systematic review on rates of relapse to alcohol dependence used in the network meta-analysis

StudyTimepoint (months)ComparatorsNumber of people relapsingNumber of people in each arm
1. ANTON199931) Placebo
2) Naltrexone
38
26
63
68
2. ANTON200531) Placebo
2) Naltrexone
47
33
80
80
3. ANTON2006121) Placebo
2) Naltrexone
3) Acamprosate
126
122
117
156
155
151
4. BALLDIN200331) Placebo
2) Naltrexone
58
53
62
56
5. BESSON1998121) Placebo
3) Acamprosate
47
41
55
55
6. CHICK2000A31) Placebo
2) Naltrexone
61
64
85
90
7. CHICK2000B61) Placebo
3) Acamprosate
242
245
292
289
8. GASTPAR200231) Placebo
2) Naltrexone
36
34
87
84
9. GEERLINGS199761) Placebo
3) Acamprosate
116
96
134
128
10. GUARDIA200231) Placebo
2) Naltrexone
19
8
99
93
11. HEINALA200131) Placebo
2) Naltrexone
54
52
58
63
12. HUANG200531) Placebo
2) Naltrexone
4
3
20
20
13. KIEFER200361) Placebo
2) Naltrexone
3) Acamprosate
32
21
22
40
40
40
14. KILLEEN200431) Placebo
2) Naltrexone
12
21
36
51
15. KRYSTAL200131) Placebo
2) Naltrexone
83
143
187
378
16. LATT200231) Placebo
2) Naltrexone
27
19
51
56
17. LEE200131) Placebo
2) Naltrexone
8
8
15
24
18. MONTI200131) Placebo
2) Naltrexone
21
18
64
64
19. MORLEY200631) Placebo
2) Naltrexone
3) Acamprosate
43
39
40
61
53
55
20. MORRIS200131) Placebo
2) Naltrexone
26
19
33
38
21. OMALLEY200831) Placebo
2) Naltrexone
28
22
34
34
22. OSLIN199731) Placebo
2) Naltrexone
8
3
23
21
23. OSLIN200861) Placebo
2) Naltrexone
76
73
120
120
24. PAILLE1995121) Placebo
3) Acamprosate
144
113
177
173
25. PELC199261) Placebo
3) Acamprosate
43
35
47
55
26. PELC199731) Placebo
3) Acamprosate
46
31
62
63
27. POLDRUGO199761) Placebo
3) Acamprosate
79
58
124
122
28. SASS199661) Placebo
3) Acamprosate
105
73
138
137
29. TEMPESTA200061) Placebo
3) Acamprosate
61
49
166
164
30. VOLPICELLI199231) Placebo
2) Naltrexone
19
8
35
35
31. VOLPICELLI199731) Placebo
2) Naltrexone
26
17
49
48
32. WHITWORTH1996121) Placebo
3) Acamprosate
139
129
224
224

From: Appendix 15, Network meta-analysis for the economic model

Cover of Alcohol-Use Disorders
Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence.
NICE Clinical Guidelines, No. 115.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2011.
Copyright © 2011, The British Psychological Society & The Royal College of Psychiatrists.

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