This figure depicts the meta-analysis of the impact of prolonged prophylaxis versus standard duration of prophylaxis on symptomatic deep vein thrombosis in patients who had major orthopedic surgery limited to trials published from 2001-present. Two trials were included in this analysis. The first trial by Eriksson and colleagues in 2003 provided an odds ratio of 0.24 with a 95 percent confidence interval of 0.05 to 1.06. The second trial by Prandoni and colleagues in 2002 provided an odds ratio of 0.64 with a 95 percent confidence interval of 0.11 to 3.72. The combined effect of the two trials showed an odds ratio of 0.36 with a 95 percent confidence interval of 0.12 to 1.12. The I-squared value could not be calculated because of too few strata.

Figure 231Impact of prolonged prophylaxis versus standard duration of prophylaxis on symptomatic deep vein thrombosis in patients who had major orthopedic surgery limited to trials published from 2001-present

I2: Too few strata

Legend: The squares represent individual point estimates. The size of the square represents the weight given to each study in the meta-analysis. Horizontal lines through each square represent 95 percent confidence intervals. The diamond represents the combined results. The solid vertical line extending from 1 is the null value.

From: Appendix G, Forest Plots

Cover of Venous Thromboembolism Prophylaxis in Orthopedic Surgery
Venous Thromboembolism Prophylaxis in Orthopedic Surgery [Internet].
Comparative Effectiveness Reviews, No. 49.
Sobieraj DM, Coleman CI, Tongbram V, et al.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.