GRADE profile 34Effectiveness of peritoneal dialysis – adverse events (adults and children)

Quality assessmentSummary of findingsQuality
No of studiesStudy designLimitationsInconsistencyIndirectnessImprecision
PD and HD (adults and children)
Adverse events
Badve 2006
Report from national registryNo serious limitationsNot assessableaNo serious indirectnessSome serious imprecisionbAdjusted weighted HR for peritonitis in PD after transplant vs PD after failure of native kidneys 0.92 (95% CI 0.72 to 1.16), after adjustment for gender, age, race, comorbidities, BMI, smoking, time from commencement of RRT to PD, country of residence; 0.88 (95% CI 0.60 to 1.30), with addition of peritoneal transport statusVERY LOW

Inconsistency not assessable (downgraded one level) because it was one study only.


Imprecise based on 10% threshold (downgraded one level).

From: 3, How this guideline was developed

Cover of Peritoneal Dialysis
Peritoneal Dialysis: Peritoneal Dialysis in the Treatment of Stage 5 Chronic Kidney Disease.
NICE Clinical Guidelines, No. 125.
Centre for Clinical Practice at NICE (UK).
Copyright © 2011, National Institute for Health and Clinical Excellence.

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