GRADE profile 32Effectiveness of peritoneal dialysis compared with haemodialysis – adverse events (adults)

Quality assessmentSummary of findingsQuality
No of studiesStudy designLimitationsInconsistencyIndirectnessImprecision
PD and HD (adults)
Adverse events
Fluck 2010
Abbott 2001
Report from national registryNo serious limitationsNot assessableaNo serious indirectnessNot assessablebMRSA
153 episodes of MRSA in 134 HD patients
No episodes reported in PD patients (although one patient had previous CAPD treatment)

Repeat episodes
123 (92%) experienced 1 episode
5 (4%) 2 episodes
4 (3%) 3 episodes
(1%) 4 episodes

OR 1.65 (95% CI 1.56 to 1.76) for septicaemia HD vs PD

Inconsistency was not assessable (downgraded one level) because outcomes were reported in one study only.


Confidence intervals only reported for some studies (and outcomes) (downgraded one level).

From: 3, How this guideline was developed

Cover of Peritoneal Dialysis
Peritoneal Dialysis: Peritoneal Dialysis in the Treatment of Stage 5 Chronic Kidney Disease.
NICE Clinical Guidelines, No. 125.
Centre for Clinical Practice at NICE (UK).
Copyright © 2011, National Institute for Health and Clinical Excellence.

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