GRADE profile 13Effectiveness of peritoneal dialysis – mortality – PD (adults and children)

Quality assessmentSummary of findingsQuality
No of studiesStudy designLimitationsInconsistencyIndirectnessImprecision
PD (adults and children)
Survival
1
Badve 2006
Report from national registryNo serious limitationsNot assessableaSome serious indirectnessbSome serious imprecisioncAdjusted weighted HR for death in PD after transplant vs PD after failure of native kidneys 1.09 (95% CI 0.81 to 1.45), after adjustment for gender, age, race, comorbidities, BMI, smoking, time from commencement of RRT to PD, country of residence; 1.32 (95% CI 0.76 to 2.31), with addition of peritoneal transport statusVERY LOW
a

Inconsistency was not assessable (downgraded one level) because it was reported in one study.

b

The study was not a comparative evaluation (downgraded one level).

c

Imprecise based on 10% threshold (downgraded one level).

From: 3, How this guideline was developed

Cover of Peritoneal Dialysis
Peritoneal Dialysis: Peritoneal Dialysis in the Treatment of Stage 5 Chronic Kidney Disease.
NICE Clinical Guidelines, No. 125.
Centre for Clinical Practice at NICE (UK).
Copyright © 2011, National Institute for Health and Clinical Excellence.

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