Table 17Input parameters utilised in the economic model of CCBT versus waitlist for people with GAD

Input parameterDeterministic valueProbabilistic distributionSource of data – comments
Clinical dataBeta distribution
Probability of non-response to treatment – waitlist0.905α = 19, β = 2TITOV2009A
Probability of relapse (both interventions)0.491α = 422, β = 437Guideline meta-analysis – pharmacological relapse prevention, pooling of placebo arms
Relative risk of non-response, CCBT versus waitlist0.41Log-normal distribution 95% CIs: 0.24 to 0.71TITOV2009A
Utility valuesBeta distribution
Response0.76α = 177.84, β = 56.16Allgulander et al., 2006; distribution estimated based on data reported in the study using the method of moments
Non-response0.63α = 24.57, β = 14.43
Relapse following response0.73α = 51.83, β = 19.17
Non-relapse following response0.79α = 97.96, β = 26.04
Cost dataGamma distribution
CCBT intervention cost£184α = 6.25, β = 29.44See Table 15
Monthly health and social care cost£67α = 2.78, β = 24.13See Table 16
Standard error of CCBT intervention cost assumed to be 40% of its mean estimate; standard error of monthly health and social care cost assumed to be 60% of its mean estimate

From: 6, LOW-INTENSITY PSYCHOLOGICAL INTERVENTIONS

Cover of Generalised Anxiety Disorder in Adults
Generalised Anxiety Disorder in Adults: Management in Primary, Secondary and Community Care.
NICE Clinical Guidelines, No. 113.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2011.
Copyright © 2011, The British Psychological Society & The Royal College of Psychiatrists.

All rights reserved. No part of this book may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers. Enquiries in this regard should be directed to the British Psychological Society.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.