Table 3.3Accuracy of models for diagnosis of ovarian malignancy on ultrasound (from Geomini et al., 2009 systematic review)

Prediction modelNSensitivity [95% CI]Specificity [95% CI]LR+LR-Probability of ovarian cancer after positive test (pre-test probability 10%)Probability of ovarian cancer after negative test (pre-test probability 10%)
Sassone18 studies, N=267084% (76% to 93%)83% (73% to 88%)4.940.1935.44%2.07%
Lerner8 studies (N not reported)90% (87% to 98%)63% (40% to 81%)2.430.1621.26%1.75%
Ferrazzi9 studies (N not reported)88% (71% to 96%)74% (59% to 89%)3.380.1627.30%1.75%
DePriest10 studies (N not reported)91% (85% to 97%)69% (60% to 78%)2.940.2924.62%3.12%
Tailor (incorporates age and colour Doppler)6 studies (N not reported)60% (20% to 100%)93% (82% to 100%)8.570.4348.78%4.56%

Abbreviations: N.R., not reported.

From: Chapter 3, Establishing the diagnosis in secondary care

Cover of Ovarian Cancer
Ovarian Cancer: The Recognition and Initial Management of Ovarian Cancer.
NICE Clinical Guidelines, No. 122.
National Collaborating Centre for Cancer (UK).
Copyright © 2011, National Collaborating Centre for Cancer.

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