Table 63Study characteristics and population: Neuroblastoma

StudyDesignMedian Age in Months (Range)Sex (M%)Histology [Site] (%)TandemSingleTreatment Period
Ladenstein, 2008;1998113, 458Cohort47 (4-744)59NR4552,8951978-2006
Kim, 2007468Case-Series36 (7-121)69NR
[Abdomen (89); Other (11)]
9271996-2004
Sung, 2007466Case-Series36 (13-129);
45.5 (24-140)a
NRFavorable (27);
Unfavorable (71);
Unknown (2)
52NA1997-2005
George, 2006459Case-Series35 (6-216)NR[Adrenal (54); Abdomen (37); Other (9)]b82bNA1994-2002
Hobbie, 2008462Case-series22 (13-72)85NR13NA1997-2001
Sung, 2010469Case-series36 (13-144) c
39 (13-159)d
46c
50d
NR71702000-2005
Matthay, 2009; 1999107, 111RCT(0-216)NRFavorable (3);
Unfavorable (63);
Unknown (33)
NA1891991-1996
Berthold, 2005105RCT(0-240)NRNRNA1491997-2002
Pritchard, 2005108RCT(6-240)50%[Abdomen (88); Other (12)]NA321982-1985

M = male; NA = not applicable; NR = not reported; RCT = randomized controlled trial

a

Age at transplant.

b

Population characteristics based on 97 study patients.

c

Tandem HSCT group.

d

Single HSCT group.

From: Systematic Reviews

Cover of Hematopoietic Stem-Cell Transplantation in the Pediatric Population
Hematopoietic Stem-Cell Transplantation in the Pediatric Population [Internet].
Comparative Effectiveness Reviews, No. 48.
Ratko TA, Belinson SE, Brown HM, et al.

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