Table 6Outcomes for older and newer antiepileptic evaluation

Comparative EfficacyGeneral Measures of Tolerance and Harms
Time to first seizure
Time to study exit due to lack of efficacy
Proportion of seizure-free patients
Proportion of patients completing the study
Proportion of patients achieving seizure remission
Seizure frequency
Proportion of patients withdrawn due to adverse events
Cosmetic adverse events
Incidence of adverse events
Incidence of individual adverse events
Incidence of adverse events resulting in therapy withdrawal

Incidence of adverse events not resulting in therapy withdrawal
Skin rash
Neurologic adverse events
Suicidal Ideation
Mortality
Medical service utilization: office/emergency department visits, hospitalizations, ambulance use

From: Methods

Cover of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy
Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy [Internet].
Comparative Effectiveness Reviews, No. 40.
Talati R, Scholle JM, Phung OJ, et al.

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