Table 37Scenario sensitivity analysis

Incremental cost per QALY
ScenarioTilt testing vs no testingTilt then IER if negative vs tiltIER vs tilt
Basecase£5,960£25,470£38,570
No survival gain from pacing after AV block observed during syncope£8,210£33,580£49,710
Bradycardia treated with pacemaker as well as asystole£6,130£24,410£35,330
Recurrences continue beyond 2 years in unpaced patients with AV block or SSS£5,800£25,320£38,450
Recurrences results in short stay admission£5,920£25,390£38,390
Continued recurrences beyond 2 years that results in short stay admission£5,590£25,130£38,370
Unpaced patients with AV block or SSS experience an average of one admission per annum£3,160£22,940£36,220
Lower limit for utility gain after pacing and no utility gain after ICD therapy£7,560£31,310£46,610
No uplift in IER device cost since 2004 (£1,400 instead of £1,600)£5,960£24,460£36,850
Costs and benefits of pacing estimated over 6 year horizon£8,590£35,690£52,640

From: 6, Diagnostic tests to direct pacing therapy

Cover of Transient Loss of Consciousness (‘Blackouts’) Management in Adults and Young People
Transient Loss of Consciousness (‘Blackouts’) Management in Adults and Young People [Internet].
NICE Clinical Guidelines, No. 109.
National Clinical Guideline Centre for Acute and Chronic Conditions (UK).
Copyright © National Clinical Guideline Centre for Acute and Chronic Conditions, 2010.

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