Table 36

No testingTiltTilt then IER if tilt negativeIER
Deterministic estimates of diagnostic outcomes per 1000 patients tested
Arrhythmia correctly paced069195145
Pacing used inappropriately020200
Missed arrhythmia that could be paced538469342392
Diagnosed VT001111
Undiagnosed VT151151140140
Other rhythm left untreated311292292311
Deterministic estimates of costs and QALYs per patient tested
Cost of testing0£117£3,780£4,020
Cost of post testing outcomes£2,240£2,660£3,750£3,410
Total costs£2,240£2,780£7,530£7,440
QALY gained4.2414.3324.5194.453
Probabilistic estimates per patient tested
Total cost£2,240£2,780£7,530£7,440
Total QALY4.2414.3324.5194.453
Incremental cost per QALY vs no testingNA£5,960£19,110£24,620
Incremental cost per QALY vs tilt testingNANA£25,470£38,570
Incremental net benefit compared to no testing at;20k per QALYNA£1,270£250£-980
£30K per QALYNA£2,170£3,020£1140
Likelihood of being optimal strategy at20k per QALY<1%94.0%<5.9%<1%
£30K per QALY<1%17.8%82.3%<1%

From: 6, Diagnostic tests to direct pacing therapy

Cover of Transient Loss of Consciousness (‘Blackouts’) Management in Adults and Young People
Transient Loss of Consciousness (‘Blackouts’) Management in Adults and Young People [Internet].
NICE Clinical Guidelines, No. 109.
National Clinical Guideline Centre for Acute and Chronic Conditions (UK).
Copyright © National Clinical Guideline Centre for Acute and Chronic Conditions, 2010.

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