GRADE profile 7Differential diagnosis of non-IgE and mixed IgE and non-IgE food allergy

StudiesDesignDiagnostic testsComparatorsType of foodDiagnosisLimitations*Inconsistency *Indirectness*Imprecision*Other ConsiderationsQuality
Outcome: differential diagnosis of non-IgE and mixed IgE and non-IgE delayed onset and immediate using combinations of tests
Six studies (Cavataio et al. 1996; Kalach et al. 2005; Ford et al. 1983; Fiocchi et al. 2004; Niggeman et al. 2000; Verini et al. 2007)ObservationalSpecific IgE antibody test, atopy patch testEndoscopy biopsy and DBPCFCCows' milk, soy, hens' eggs, wheat, peanutsConflicting results. No clear-cut differential diagnosis. Studies more definite on IgE and very vague on non-IgEYYYYNVery low
*

Please see footnotes 7131410 for criteria for downgrading

From: 2, How this guideline was developed

Cover of Food Allergy in Children and Young People
Food Allergy in Children and Young People: Diagnosis and Assessment of Food Allergy in Children and Young People in Primary Care and Community Settings.
NICE Clinical Guidelines, No. 116.
Centre for Clinical Practice at NICE (UK).
Copyright © 2011, National Institute for Health and Clinical Excellence.

All rights reserved. This material may be freely reproduced for educational and not-for-profit purposes. No reproduction by or for commercial organisations, or for commercial purposes, is allowed without the express written permission of NICE.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.