Clinical settingPatients with metastatic adenocarcinoma or undifferentiated carcinoma whose primary had not been identified by clinical history, physical examination or chest x-ray. Patients presented to a single institution between 1977 and 1982.
Participants and Country286 patients. 177 had metastases histology: 68 adenocarcinoma, 64 poorly differentiated adenocarcinoma and 54 undifferentiated carcinoma. Australia
Study designRetrospective case series.
Target conditionIdentification of the primary tumour. Primary site was histologically confirmed in a subset of patients.
TestsGastroscopy (N=21) and sigmoidoscopy (N=26) (amongst other tests)
Follow upnot reported

From: Guideline chapter 2, Diagnosis

Cover of Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin.
NICE Clinical Guidelines, No. 104.
National Collaborating Centre for Cancer (UK).
Copyright © 2010, National Collaborating Centre for Cancer.

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