Clinical settingTest designed to identify tumour markers for use in patients with adenocarcinoma of unknown primary.
Participants and CountryNot applicable
Study designDiagnostic test development study
Target conditionTissue of origin of the primary tumour. Only tumours of known primary were included.
TestsRT-PCR using 11 genes.
Follow upNot applicable
Commercially available assayNone
Bioinformatic strategyHierarchical clustering
Validation methodIndependent validation set of nine tissue samples from adenocarcinomas and the LNCaP prostate adenocarcinoma cell line

From: Guideline chapter 2, Diagnosis

Cover of Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin.
NICE Clinical Guidelines, No. 104.
National Collaborating Centre for Cancer (UK).
Copyright © 2010, National Collaborating Centre for Cancer.

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