MethodsRetrospective case series of CUP patients who received either short course or long-course WBRT for brain metastases
Participants and Country101 patients with CUP.
InterventionsShort course WBRT (n=34) long-course WBRT (n=67)
OutcomesOverall survival, intracerebral control
WBRT fractionationShort-course RT was 20 Gy in 5 fractions (5 × 4 Gy) given over 5 days. Long course WBRT was 10 × 3 Gy given over 2 weeks or 20 × 2 Gy given over 4 weeks.
NotesPaper not in file

From: Guideline chapter 4, Specific Presentations

Cover of Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin.
NICE Clinical Guidelines, No. 104.
National Collaborating Centre for Cancer (UK).
Copyright © 2010, National Collaborating Centre for Cancer.

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