Table E.1Disimpaction treatments, mean times to disimpaction, mean daily doses

Mean time to disimpact (days)Data sourceMean doses for disimpactionData source for doses and unit costs
Group 1
PEGa 3350 plus electrolytes baseline dose4GDG members4 sachets dailyBNFCb
PEG 3350 plus electrolytes higher dose4GDG members7.5 sachets dailyBNFC
PEG 3350 plus electrolytes + sodium picosulfate4GDG membersSee baseline dosesBNFC
Group 2BNFC
Picosulfate baseline dose4GDG members2.5 mg dailyBNFC
Picosulfate higher dose4GDG members5 mg dailyBNFC
PEG 3350 plus electrolytes + sodium picosulfate4GDG membersSee baseline dosesBNFC
Picosulfate + senna4GDG membersSee baseline dosesBNFC
Picosulfate +lactulose4GDG membersSodium picosulfate: see baseline dose
Lactulose: 10 ml daily
BNFC
Group 3
Senna baseline dose24GDG members2.5 ml dailyBNFC
Senna higher dose24GDG members5 ml dailyBNFC
Picosulfate + senna4GDG membersBNFC
Lactulose + senna24GDG membersLactulose: 10 ml daily
Senna: see baseline dose
BNFC
Docusate + senna24GDG membersDocusate: 12.5 ml 3 times daily
Senna: see baseline dose
BNFC
Group 4
Enemas1GDG members5 ml dailyBNFC
NHS reference costs 2006/7
Manual evacuation
1GDG membersn/aNHS reference costs 2006/7
a

PEG: polyethylene glycol

a

BNF for Children (BNFC) website last accessed December 2008

From: Appendix E, Health economics

Cover of Constipation in Children and Young People
Constipation in Children and Young People: Diagnosis and Management of Idiopathic Childhood Constipation in Primary and Secondary Care.
NICE Clinical Guidelines, No. 99.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2010.
Copyright © 2010, National Collaborating Centre for Women's and Children's Health.

No part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK [www.cla.co.uk]. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.