Evidence About Sensitivity And Specificity Of Imaging Modalities

Imaging ModalitySensitivitySpecificity
MRI44 – 100%
(Andreasson et al. 1990, Colletti et al 1991, Colletti et al 1996, Jung et al 2003 (Compression Fractures), Loblaw et al 2005)
90 – 93%
(Andreasson et al 1990, Colletti et al 1991, Colletti et al 1996, Jung et al 2003 (Compression Fractures), Loblaw et al 2005)
Bone Scintigraphy19 – 100%
(Levack et al 2002, Andreasson et al 1990, Colletti et al 1991)
100%
(Levack et al 2002, Andreasson et al 1990, Colletti et al 1991)
CTLesion based: 68–78%
Patient based: 50% (Metser et al 2004)
Lesion based: 56%
Patient based: 50% (Metser et al 2004)
CT/MyelographyAll relevant studies identified by search (n=3) were dated 1991, 1992, 1995. This will not reflect a modern CT scan. Therefore results were not extracted and included in Evidence Table.

No evidence for modern CT/Myelography was identified.
PET/CTOnly one study was identified from the search, Metser et al 2004.
The following was extracted from this study:
18F-FDG PET/CT performed on patients with malignant involvement of the spinal column has better specificity than does 18F-FDG PET alone. PET/CT enables precise localization of lesion level in the vertebral column and (essential for optimal treatment planning) identification of potentially neurologically significant soft- tissue abnormalities. (Metser et al.2004)

From: Chapter 5, Choice of Imaging

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Metastatic Spinal Cord Compression: Diagnosis and Management of Patients at Risk of or with Metastatic Spinal Cord Compression.
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