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Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

Diffuse malignant peritoneal mesothelioma: Systematic review of clinical management and biological research

Review published: 2011.

Bibliographic details: Baratti D, Kusamura S, Deraco M.  Diffuse malignant peritoneal mesothelioma: Systematic review of clinical management and biological research. Journal of Surgical Oncology 2011; 103(8): 822-831. [PubMed: 21283990]

Abstract

Diffuse malignant peritoneal mesothelioma (DMPM) is an uncommon and locally aggressive tumor with poor prognosis. Currently, no standard therapy is available. The biology of this disease is still poorly understood. We performed a systematic search of relevant studies on clinical management and biological research of DMPM. Trials were selected using a predetermined protocol. The current evidence suggests that cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC) results in improved survival. Biological understanding of DMPM is currently evolving.

Copyright © 2011 Wiley-Liss, Inc.

CRD has determined that this article meets the DARE scientific quality criteria for a systematic review.

Copyright © 2014 University of York.

PMID: 21283990

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