Table 5.10.7Changes in REM and slow wave sleep (%) in randomized controlled trials of mandibular advancement devices vs. inactive oral devices

Study
PMID
Baseline AHI (SD) [eligibility]Baseline ESS (SD)Duration (design)OutcomeInterventionsNo. AnalyzedBaseline (SD)Change (Final)Net diff or Diff95% CIP BtwDropout %Study Quality
Mehta 2001218
11371418
27 (17) [10–68]nd1 wk (XO)REMMAD24nd2151.5, 8.5 *<0.00514B
Lower dental plate24nd16
Petri 2008212
18482111
35 (nd) [>5]11.0 (nd)4 wk (PL)REMMAD2718.4 (5.6)0.3−0.4−3.7, 2.9 nd9B
Non- advancement MAD2516.8 (7.5)0.7
Stage 3MAD277 (5)2.12.90.1, 5.7 nd
Non- advancement MAD259.9 (5.1)−0.8
Stage 4MAD2710.2 (10.5)2.2−1.2−6.6, 4.2 §nd
Non- advancement MAD259.6 (10.3)3.4
*

Estimated from reported P value

Estimated from reported data

Estimated from reported P value

§

Estimated from reported data

From: Appendix D, Summary Tables

Cover of Diagnosis and Treatment of Obstructive Sleep Apnea in Adults
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults [Internet].
Comparative Effectiveness Reviews, No. 32.
Balk EM, Moorthy D, Obadan NO, et al.

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