Table 5.11.6Outcomes randomized controlled trials of mandibular advancement devices vs. tongue-retaining devices

Study
PMID
Baseline AHI (SD) [eligibility]Baseline ESS (SD)Duration (design)OutcomeInterventionsNo. AnalyzedBaseline (SD)Change (Final)Net Diff or Diff95% CIP BtwDropout, %Study Quality
Deane 2009222
19480232
27.0(nd) [>10]nd1 wk (XO)AHIMAD2227 (17)−15−1−9.7, 7.7 *nd19B
TSD2227 (17)−14
Minimum O2 satMAD2284 (7)3−1−4.7, 2.7 nd
TSD2284 (7)4
Arousal indexMAD2233 (16)−120ndnd
TSD2233 (16)−12
Sleep efficiencyMAD2280 (11)−2−1−8.7, 6.7 nd
TSD2280 (11)−1
REMMAD22nd181ndNS
TSD22nd17

Estimated from reported data

*

Estimated from reported data

Estimated from reported data

From: Appendix D, Summary Tables

Cover of Diagnosis and Treatment of Obstructive Sleep Apnea in Adults
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults [Internet].
Comparative Effectiveness Reviews, No. 32.
Balk EM, Moorthy D, Obadan NO, et al.

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