Table 13-5Tablet desmopressin compared to imipramine for children with night and daytime wetting - Clinical summary of findings

OutcomeTablet desmopressinImipramineRelative risk (95% CI)Absolute effectQuality
Number of children who had 0-1 wet nights per month9/26 (34.6%)3/25 (12%)RR 2.88 (0.88 to 9.44)226 more per 1000 (from 14 fewer to 1000 more)VERY LOW
Mean number of wet nights per week at end of treatment2625-MD −1.4 (−2.25 to − 0.55)VERY LOW

From: 13, Desmopressin and the management of bedwetting

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
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