Table 13-19Tablet desmopressin compared to tablet desmopressin and enuresis alarm for children with bedwetting - Clinical summary of findings

OutcomeTablet desmopressinTablet desmopressin and enuresis alarmRelative risk (95% CI)Absolute effectQuality
Number of children who achieved 14 consecutive dry nights16/38 (42.1%)20/32 (62.5%)RR 0.67 (0.43 to 1.07)206 fewer per 1000 (from 356 fewer to 44 more)LOW
Mean number of wet nights per week at end of treatment3629-MD 1.4 (0.35 to 2.45)LOW
Number of children who relapsed at 3 months9/16 (56.3%)7/20 (35%)RR 1.61 (0.77 to 3.36)214 more per 1000 (from 81 fewer to 826 more)LOW
Number of children who dropped out by end of trial2/38 (5.3%)3/32 (9.4%)RR 0.56 (0.1 to 3.15)41 fewer per 1000 (from 85 fewer to 202 more)LOW

From: 13, Desmopressin and the management of bedwetting

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
Copyright © 2010, National Clinical Guideline Centre.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

The rights of the National Clinical Guideline Centre to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.