Table 15-9Imipramine compared to desmopressin and oxybutynin - Clinical summary of findings

OutcomeImipramineDesmopressin and oxybutyninRelative risk (95% CI)Absolute effectQuality
Number of children who had 0–1 wet nights per month3/25 (12%)9/26 (34.6%)RR 0.35 (0.11 to 1.13)225 fewer per 1000 (from 308 fewer to 45 more)VERY LOW
Mean number of wet nights per week at the end of treatment2526-MD 1.43 (0.45 to 2.41)VERY LOW

From: 15, Tricyclic medication and the management of bedwetting

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Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
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