Table 1.5-9Dry bed training with an alarm with therapist at home compared to dry bed training with an alarm with therapist at hospital - Clinical study characteristics

OutcomeNumber of studiesDesignLimitationsInconsistencyIndirectnessImprecision
Number of children who achieved 14 consecutive dry nights1randomised trialvery serious1no serious inconsistencyno serious indirectnessno serious imprecision
Mean number of wet nights per week at the end of treatment (no sd)1randomised trialvery serious1,2no serious inconsistencyno serious indirectnessserious3
Number of children who relapsed1randomised trialvery serious1no serious inconsistencyno serious indirectnessserious4

Bollard 1981 had an unclear blinding method and unclear allocation concealment


Results from Cochrane review - paper did not present this result


No information on variability was given in the study, therefore calculation of standard deviation was not possible and the mean difference and CI were not estimable


The confidence interval crosses the MID(s)

From: Appendix H, GRADE profile tables

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
Copyright © 2010, National Clinical Guideline Centre.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

The rights of the National Clinical Guideline Centre to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.