Table 1.11-1Enuresis alarm compared to DBT for children resistant to enuresis alarms - Clinical study characteristics

OutcomeNumber of studiesDesignLimitationsInconsistencyIndirectnessImprecision
Number of children who achieved 14 consecutive dry nights2randomised trialvery serious1,2no serious inconsistencyno serious indirectnessserious3
Mean number of wet nights per week at the end of treatment (no sd)2randomised trialvery serious1,4no serious inconsistencyno serious indirectnessserious5
Number of children who relapsed2randomised trialvery serious1,2no serious inconsistencyno serious indirectnessserious3
Number of children who dropped out1randomised trialvery serious1,6no serious inconsistencyno serious indirectnessserious3
1

Studies had unclear allocation concealment and blinding

2

Result from Butler (1988) from Cochrane review

3

The confidence interval crosses the MID(s)

4

Results from Butler (1988) and Butler (1990) taken from the Cochrane review

5

No information on variability was given in the study, therefore calculation of standard deviation was not possible

6

The study had unclear allocation concealment and blinding

From: Appendix H, GRADE profile tables

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
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