Table 6-2Main findings from studies listed in table 6-1 Assessment

AuthorSettingOutcomePrevalenceImpact on treatment
Van Der Vismelsen (1992)44Netherlands% of children with radiographic abnormalitiesNo comparison groupNot reported
Yeung (2004)45Enuresis clinic, Hong KongRelationship between bladder wall thickness and bladder volume in response to desmopressinNot reportedChildren with a thicker bladder wall were less likely to respond to desmopressin. Children with a larger bladder volume were more likely to respond to desmopressin
Redman (1979)46University Hospital, USANumber of children with abnormalitiesNo comparison groupNot reported
Cutler (1978)47Primary Medical Centre, USARadiographic abnormalities and surgeryNo comparison groupNot reported
Yeung (1999)48Hospital, ChinaPattern of NE based on urodynamic findingsNo comparison groupNo clear trend in response to desmopressin
Sujka (1991)49Department of Urology, Buffalo, USAPatients with or without refluxNo statistically significant difference in characteristics between children with reflux and children without refluxNot reported
Tanaka (2003)50Outpatient clinic, JapanRate of reflux between MNE and NMNE, prognosis after 2 years (treatment with anticholinergics)A positive history of NE in siblings and frequency were both statistically more common in children with refluxChildren who responded to treatment showed no statistical difference in the number of children with or without reflux
Zink (2008)51University Hospital, GermanyDifferences in CBCL score, ICD-10 score, uroflow, ultrasound residual urine, bladder wall thicknessNMNE patients had statistically more residual urine and thicker bladder wallNot reported
Cayan (2001)52Day care centres and schools, TurkeyDifferences between MNE patients and controlsStatistically significantly more children with MNE had constipationNot reported
McGrath (2008)53Clinic, Hospital, AustraliaNumber of children with constipationStatistically more children who had failed treatment with an alarm were constipated; poor level of agreement between parental reporting of constipation and clinical resultsNot reported
O'Regan (1986)54University, CanadaImpact of treatment of constipation22 out of 25 children had constipationTreatment for constipation lead to children becoming initially dry
Butler (2004)55Outpatients for NE at Hospital, UKPredictive factors in successful treatment with desmopressin or anticholinergics from the 3 systems approachNot reportedNo predictive factors for desmopressin; predictive factors for successful treatment with anticholinergics was: age, frequency, passing small voids, small or variable wet patches, wakes soon after voiding
Siegel (1976)56USANE in UTI and allergy patientsThere was no statistical difference between the number of children with persistent NE (night wetting every week) and children previously treated for UTI and controls. There was no statistical difference between the number of children with persistent NE (night wetting every week) and children with allergies and controlsNot reported
Robson (2005)57University Hospital, USADifferences between PNE and SNEConstipation statistically more prevalent in SNENot reported
Nappo (2002)58Centres in Italy% results of number of children with characteristicNo comparison groupNo statistically significant difference in the following variables between those who responded to desmopressin and those who did not: gender, age, family history, frequency of NE (number of wet nights per week)
Bladder Diaries
Kwak (2008) 62Hospital, KoreaDifferences in bladder diaries and questionnaireNo similarities in the results of bladder diaries or questionnaireNot reported
Van Hoacke (2004)60Paediatric urology / nephrologic Centre, Hospital, BelgiumDifferences in scales and questionnairesCBCL score: children with NE are more withdrawn and anxious / depressive; Other scores: children with NE had difference social desirability scoreNot reported
Van Hoacke (2007)61Tertiary careScores on CBCL, DBDRS scales, and sensitivity / specificityNo comparison groupNot reported

From: 6, Assessment for children with Bedwetting

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
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