Table 8-116Separate combination of prostaglandin analogues plus beta-blockers versus prostaglandin analogues - Clinical summary of findings

OutcomeInterventionControlRelative riskAbsolute effectQuality
Mean change in IOP from baseline7981not applicableMD −0.66 (−1.44 to 0.13)Very low
Number of patients with an acceptable IOP of approx <18mmHg30/45 (66.7%)32/46 (69.6%)RR 0.96 (0.72 to 1.27)28 fewer per 1000 (from 195 fewer to 188 more)Low
Number of patients experiencing a respiratory adverse event1/49 (2%)0/50 (0%)RR 3.06 (0.13 to 73.34)not estimable (a)Very low
Number of patients with hyperaemia27/79 (34.2%)18/81 (22.2%)RR 1.54 (0.98 to 2.44)120 more per 1000 (from 4 fewer to 320 more)Very low
a

An absolute effect calculation is not possible as there are no events in the control arm of the study.

From: 8, Treatment of chronic open angle glaucoma

Cover of Glaucoma
Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension.
NICE Clinical Guidelines, No. 85.
National Collaborating Centre for Acute Care (UK).
Copyright © 2009, National Collaborating Centre for Acute Care.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

The rights of National Collaborating Centre for Acute Care to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.