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National Collaborating Centre for Acute Care (UK). Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension. London: National Collaborating Centre for Acute Care (UK); 2009 Apr. (NICE Clinical Guidelines, No. 85.)

9Complementary and alternative interventions

9.1. Introduction

This chapter addresses approaches other than the mainstream interventions that are directed towards the lowering of IOP. The GDG decided to investigate the effectiveness of neuroprotective agents as a possible alternative to IOP lowering treatments. These agents attempt to preserve those cells which have been adversely affected by a glaucoma ‘insult’ and remain vulnerable to damage73. A variety of pharmacological agents, growth factors, and other compounds have been reported to be neuroprotective in vitro, and in a number of neurologic and neurodegenerative disorders.

An initial search was also undertaken to identify other candidate complementary and alternative treatments for OHT and COAG. Two reviews120,122 suggested that a range of treatments may be of value for glaucoma patients.

We conducted a subsequent search for evidence on the following interventions and approaches in patients with OHT and COAG.:

9.2. Complementary and alternative treatments

We searched for RCT evidence investigating the effectiveness of these interventions using the same criteria which were applied for evidence supporting the medical, laser and surgical interventions.

9.2.1. Comparison of complementary and alternative treatments used alone or as an adjuvant

9.2.1.1. Clinical evidence

No studies meeting the inclusion criteria for any of the treatments mentioned above were identified

9.2.1.2. Economic evidence

No studies meeting the inclusion criteria for any of the treatments mentioned above were identified

9.2.1.3. Patient views evidence

No studies were identified

9.3. Conclusions

In the absence of objective scientific evidence supporting the use of these approaches the consensus view of the GDG was sought. It was decided that without either supportive evidence or accepted practice it was not possible to form an opinion either in support of or against the use of the identified candidate complementary and alternative treatments for glaucoma. As such, no recommendations on these interventions have been made.

Copyright © 2009, National Collaborating Centre for Acute Care.

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Cover of Glaucoma
Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension.
NICE Clinical Guidelines, No. 85.
National Collaborating Centre for Acute Care (UK).

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