Drummond Checklist (of Included Studies)

QuestionBotteman et al 2006Ross et al 2004 (HTA report)De Cock 2005aDe Cock 2005bHillner et al 2000Dranitsaris et al 1999
1. The research question is stated.YesNot fullyYesYesYesYes
2. The economic importance of the research question is stated.YesYesYesYesYesYes
3. The view point(s) of the analysis are stated and justified.YesYesYesYesNot fullyYes
4. The rationale for choosing the alternative programmes or interventions are stated.YesNot fullyNot fullyNot fullyYesYes
5. The alternatives being compared are clearly described.Not clearNoYesYesNoYes
6. The form of economic evaluation is stated.Not clearNoYesYesNoYes
7. The choice of form of economic evaluation is justified in relation to the questions addressed.NoNoYesYesNoNo
8. The source(s) of effectiveness estimates are stated.YesYesYesYesYesYes
9. Details of the design and results of effectiveness study are given (if based on a single study).NoYesNoNoYesYes
10. Details of methods of synthesis or meta-analysis of estimates are given (if based on an overview of a number of effectiveness studies).NoNoNoNoNot applicableNot applicable
11. The primary outcome measure(s) for the economic evaluation are clearly stated.YesYesYesYesYesYes
12. Methods to value health states and other benefits are stated.YesYesYesYesYesYes
13. Details from the subjects from whom valuations are obtained are given.NoNoNoNoYesYes
14. Productivity changes (if included) are reported separately.Not applicableNot applicableNot applicableNot applicableNot applicableNot applicable
15. The relevance of productivity changes to the study question is discussed.NoNot applicableNoNoYesNo
16. Quantities of resources are reported separately from their unit costs.YesYesYesYesYesNo
17. Methods for the estimation of quantities and unit costs are described.YesYesYesYesNot fullyYes
18. Currency and price data are recorded.NoYesNoNoNoYes
19. Details of currency of price adjustments for inflation or currency conversion are given.NoNot applicableNot applicableNot applicableNoYes
20. Details of any model used are given.YesYesNot clearNot clearNot clearYes
21. The choice of model used and key parameters on which it is based are justified.NoYesNoNoNoYes
22. The horizon of costs and benefits is stated.YesYesNoNoYesYes
23. The discount rate is stated.YesYesNoNoYesYes
24. The choice of rate is justified.YesYesNoNoNot applicableNot applicable
25. An explanation is given if costs or benefits are not discounted.NANANoNoYesYes
26. Details of statistical test and confidence intervals are given for stochastic data.YesNoNoNoNoNot fully
27. The approach to sensitivity analysis is given.YesYesYesYesNot fullyYes
28. The choice of variables for sensitivity analysis is justified.NoYesYesYesYesNo
29. The ranges over which the variables are varied is stated.YesYesNoNoNoYes
30. Relevant alternatives are compared.YesYesYesYesYesYes
31. Incremental analysis is reported.YesYesYesYesNot clearYes
32. Major outcomes are reported in a disaggregated as well as aggregated form.YesYesYesYesYesYes
33. The answer to the study question is given.YesYesYesYesYesYes
34. Conclusions followed from the data reported.YesYesYesYesYesYes
35. Conclusions are accompanied by the appropriate caveats.YesYesYesYesYesYes
36. Generalisability issues are addressed.NoYesYesYesNoNo

From: Chapter 6, Management of specific problems

Cover of Advanced Breast Cancer
Advanced Breast Cancer: Diagnosis and Treatment.
NICE Clinical Guidelines, No. 81.
National Collaborating Centre for Cancer (UK).
Copyright © 2009, National Collaborating Centre for Cancer.

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