Dietary factors (caffeine and fluid intake) (2 of 2 tables)

StudyStudy type and ELAim of studyNo. of patientsPatient characteristicsOutcomesResultsAdditional comments
Wyman 1991206Case series
EL = 3
To investigate an association between fluid intake and voiding patterns over 1 week126F ≥ 55 years with UI who were enrolled in a study of behaviour management (Fantl 1991, n = 126).205 Urodynamic diagnosis: 29% DO, 71% stress UICorrelation between fluid intake and urinary outcomesr = 0.38, P = 0.0001 diurnal frequency
r = 0.22, P = 0.02 nocturnal frequency
r = 0.34, P = 0.0001 leakage
Funding: National Institute for Aging, National Centre for Nursing Research, National Institutes of Health.
Mean fluid intake 1.7–1.8 litres/day in each diagnostic group.
Creighton 1990196Before and after study
EL = 3
An investigation of the urodynamic effects of 200 mg caffeine (twin-channel cystometry and uroflowmetry, 30 mins after intake)3020 women with DO; symptoms exacerbated by caffeine containing drinks
10 asymptomatic women (controls)
Pressure rise on filling (cmH2O) unclear whether mean or medianCases:
With caffeine 17 (0–42)
without caffeine 11 (0–25), P < 0.03
2 (0.5)
Funding: none declared.
No sig. changes in other urodynamic parameters in either group.
Tomlinson 1999197Case series
EL = 3
Evaluate relationship between caffeine intake and UI, during the initial 2–4 week self-monitoring phase of a behaviour management programme (one arm of a RCT199 described in the behavioural management section)34F ≥ 55 years with UI (≥ 2 episodes/week)Caffeine intake/day*Fell: 900 to 480 ml (47%)Funding: National Institutes of Nursing Research, National Institutes of Health, Johnson and Johnson supplied ‘products’.
*all median changes for women who were encouraged to reduce caffeine intake specifically.
change in caffeine intake not significantly associated with change in any outcome (standard linear regression analysis).
Fluid intake/dayIncreased: 1680 to 1870 (11%)
Urine loss/dayFell: 23.4 g to 14.2 g (39%)
Daytime leakage episodes/dayFell: 2.33 to 1.0 (57%)
Voiding interval, h/daytimeFell: 2.26 to 2.18 (4%)
James 1989198Case series
EL = 3
Investigate effects of chronic caffeine intake on UI in psychogeriatric patients with UI14 (8 women)M/F, 64–89 years, psychogeriatirc patients who underwent a 13-week programme of alternating caffeine intake or abstinenceDay leakage episodes (mean, SD)Caffeine intake*:
4.38 (1.57); 4.71 (1.29)
Caffeine free:
2.85 (1.16); 3.14 (1.17)
Funding: none declared.
*2 periods of caffeine intake, 2 caffeine-free periods.
Night leakage episodes (mean, SD)Caffeine intake*:
2.5 (0.34); 2.56 (0.27)
Caffeine free:
1.91 (0.25); 2.10 (0.23)

From: Evidence tables for included studies

Cover of Urinary Incontinence
Urinary Incontinence: The Management of Urinary Incontinence in Women.
NICE Clinical Guidelines, No. 40.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2006 Oct.
Copyright © 2006, National Collaborating Centre for Women’s and Children’s Health.

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