Intramuscular glucagon compared with subcutaneous glucagon

Aman and Wranne, 1988489Children and young people with induced hypoglycaemia (n = 30)
Age intramuscular 12.2 ± 3.0, subcutaneous: 11.8 ± 3.2 years
Intramuscular glucagon 20 μg/kg body weight
subcutaneous glucagon 20 μg/kg body weight
  1. Blood glucose concentrations
  2. Plasma glucagon concentrations
  1. No difference
  2. No difference
No description of how randomisation took place
No details of blinding of the study
Does induced hypoglycaemia act in the same way as accidental hypoglycaemia?
RCT crossoverIb

From: Evidence tables

Cover of Type 1 Diabetes
Type 1 Diabetes: Diagnosis and Management of Type 1 Diabetes in Children and Young People.
NICE Clinical Guidelines, No. 15.2.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2004 Sep.
Copyright © 2004, National Collaborating Centre for Women’s and Children’s Health.

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