Figure 10 depicts a meta-analysis 2 of specificity of genotyping TPMT *2, *3A, and *3C, to diagnose TPMT activity. The figure is divided into three columns with the heading reading left to right: Study, Specificity‡, and Specificity (95 percent confidence interval). From left to right, the results are: Gardiner, 2008--68/68--99.3 (89.5, 100); Ansari, 2002--40/40--98.8 (83.3, 99.9);Mazrinaki, 2003--85/85--99.4 (91.4, 100); Pooled results-- 99.2, (96.2, 99.8)

Figure 10Meta-analysis 2 of specificity of genotyping TPMT *2, *3A, and *3C, to diagnose TPMT activity

‡ (Noncarriers (wild type) and/or heterozygotes with normal/intermediate/high enzymatic activity) (all with normal, intermediate or high enzymatic activity)

From: 3, Results

Cover of Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs
Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs.
Evidence Reports/Technology Assessments, No. 196.
Booth RA, Ansari MT, Tricco AC, et al.

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