Table A16-3Validation therapy vs. standard care for the treatment of cognitive symptoms of dementia

Quality assessmentSummary of findings
No of patientsEffectQualityImportance
No of studiesDesignLimitationsConsistencyDirectnessOther considerationsvalidation therapystandard careRelative (95% CI)Absolute (95% CI)
MOSES:Self care (Toseland (1997) Range: to . Better indicated by: higher scores)
1Randomised trialsSerious limitations (− 1)2No important inconsistencyNo uncertaintyImprecise or sparse data (−1)1,42322-WMD −1.09 (−4.00 to 1.82)⊕⊕○○
Low
9
Cognition (Mental Status Questionnaire (Robb 1986); MOSES: Disorientation (Toseland 1997) Range: to . Better indicated by: lower scores)
2Randomised trialsSerious limitations (− 1)2No important inconsistencyNo uncertaintyImprecise or sparse data (−1)53234-SMD −0.35 (−0.84 to 0.14)⊕⊕○○
Low
9
1

One study

2

No concealment of allocation

3

No blinding

4

Confidence intervals both sides of the line of no effect

5

Two small studies

From: APPENDIX 16, EVIDENCE PROFILE TABLES FOR QUANTITATIVE REVIEWS

Cover of Dementia
Dementia: A NICE-SCIE Guideline on Supporting People With Dementia and Their Carers in Health and Social Care.
NICE Clinical Guidelines, No. 42.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2007.
Copyright © 2007, The British Psychological Society & The Royal College of Psychiatrists.

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