Study descriptions

TitleAuthor(s)YearStudy TypeGradingParticipants or included studiesInclusion/exclusionDescription of participants/studiesRecruitmentSettingAimsComparisonsLength of studyOutcomes
Association between the current use of low- dose oral contraceptives and cardiovascular arterial disease: a meta- analysisBaillargeon JP; McClish DK; Essah PA; Nestler JE;2005MET1−14 case control studies
Epidemiology of oral contraceptives and cardiovascular disease.Chasan-Taber L; Stampfer MJ;1998SR1+All english language epidemiological studies
Oral contraceptives use and the risk of myocardial infarction: a meta-analysisKhader YS; Rice J; John L; Abueita O;2003MET1−19 case control; 4 cohort
The effect of rosuvastatin on oestrogen & progestin pharmacokinetics in healthy women taking an oral contraceptiveSimonson SG; Martin PD; Warwick MJ; Mitchell PD; Schneck DW;2004COH2+18Healthy volunteers; pre- menopausal; nonpregnant, nonbreastfeeding, nonsmoking between 18–40 with intact ovarian function who had received ortho tri cyclen throughout the previous 3 menstrual cycles. Exclusion criteria included elevated liver enzymesFemale, with mean age of 25, height 163 cm and weigh of 60kg.VolunteersFinlandEffect of rosuvastatin on estrogen and progestin metabolism.Changes in hormone levels of estrogen, progestin FL, FSH, cortisol and TC, LDL-C, TG nd HDL.Two menstrual cyclesHormone concentrations and lipid levels
Myocardial infarction and third generation oral contraceptives: Aggregation of recent studiesSpitzer WO; Faith JM; MacRae KD;2002MET1−Case control

From: Appendix C, Clinical data extractions and excluded studies

Cover of Identification and Management of Familial Hypercholesterolaemia (FH)
Identification and Management of Familial Hypercholesterolaemia (FH) [Internet].
NICE Clinical Guidelines, No. 71.
National Collaborating Centre for Primary Care (UK).
Copyright © 2008, Royal College of General Practitioners.

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