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Long-acting Reversible Contraception: The Effective and Appropriate Use of Long-Acting Reversible Contraception

Long-acting Reversible Contraception: The Effective and Appropriate Use of Long-Acting Reversible Contraception

NICE Clinical Guidelines - National Collaborating Centre for Women’s and Children’s Health (UK)

Version: October 2005

Evidence Tables

Usage of implants and injectables

Progestogen-only subdermal implants (POSDIs)

Contraceptive implants are inserted subdermally under the skin in the upper arm. Implanon Update 2013: The progestogen-only subdermal implant, Implanon, recommended in this guideline is no longer available. Implanon was replaced by Nexplanon. Nexplanon contains the same amount of the same drug as Implanon, but the summaries of product characteristics for the two devices are not identical. In the light of the change in the implant available, NICE will review the evidence and update the section of the guideline that makes recommendations on progestogen-only subdermal implants. All recommendations that refer to Implanon should be accompanied by a footnote which states the following: “The progestogen-only subdermal implant (Implanon) recommended in this guideline is no longer available. Healthcare professionals considering offering the replacement device, Nexplanon, should refer to the summary of product characteristics.” is currently the only subdermal implant licensed for use in the UK. Norplant has not been marketed in the UK since 1999. However, it is still in use in many other countries and women still attend UK clinics requesting removal. Jadelle® (Norplant-2) has not been marketed in the UK, but is licensed elsewhere in the world and women sometimes attend UK clinics requesting removal.

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