10.1.6What are the outcomes associated with these antibiotic regimens?

StudyRef.PopulationInterventionOutcomesResultsCommentsStudy typeEL
Villar et al., 2001352Cochrane systematic review, updated 2000
8 RCTs comparing different antibiotic regimens
2 RCTs
Single dose compared with 4 to 7 day courseGastrointestinal side effectsTreatment group: 16/231 (6.9%)
Control group: 29/209 (14%)
Peto odds ratio: 0.53 (95% CI 0.31 to 0.91)
Results largely influenced by a trial that was stopped mainly due to side effects of sulphadimidineSR1a

From: Evidence tables

Cover of Antenatal Care
Antenatal Care: Routine Care for the Healthy Pregnant Woman.
NICE Clinical Guidelines, No. 62.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2008 Mar.
Copyright © 2008, National Collaborating Centre for Women’s and Children’s Health.

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