Table 10.1Comparison of rhythm-control treatments for post-op AF with rate-controlling treatments or no treatment in terms of percentage of patients reverting to sinus rhythm

ComparisonNPeriod (hours)Rhythm (%)Control (%)p
(1+)Flecainide/digoxin255291600<0.001
(1+)Propafenone/placebo250141430<0.001
(1+)Procainamide/digoxin25230129360<0.05
(1+)Sotalol/digoxin*25340128585NS
(1+)Propafenone/various**25132243550NS
(1+)Amiodarone/digoxin25430249387NS
*

Digoxin with additional disopyramide if sinus rhythm was not restored within 2 hours.

**

Various = uncontrolled use of beta-blockers, calcium antagonists or digoxin in both treatment arms.

From: 10, Postoperative AF

Cover of Atrial Fibrillation
Atrial Fibrillation: National Clinical Guideline for Management in Primary and Secondary Care.
NICE Clinical Guidelines, No. 36.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2006, Royal College of Physicians of London.

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