Scoring system for MSL

Bibliographic reference Study type Evidence level Number of patients Patient characteristics Intervention Comparison Length of follow-up Outcome measures Effect size Source of funding Additional comments
Morad Y;Kaplan B;Zangen S;Rabinerson D;Peleg D;Merlob P; 1998461CohortEvidence level: 2+Intervention N=80
Controls N=100

(NB. Omparison of these 2 groups doen using t- tests inc. for Apgar scores and estimation of mec thickness - not appropriate)
Babies born with meconium staining (? Same as MSL)Intervention: Scoring system for immediate assessment of babies born with MSLComparison: Use of scoring system with historic controls with no scoring system and routine use or laryngoscopy for visualisation of glottis and endotracheal intubation and suctionng when mec staining of cords observed.Follow-up period: Until discharged home from NICU/hospitalOutcome Measures: Main: Meconium aspiration syndrome
Other outcomes: Intubation, positive mec suction, MAS, MAS necessitating assisted ventilation
Study group vs. controls:
MAS 5% vs. 6% NS
MAS necessitating ventilation: 2.5% vs. 2% NS Positive meconium suction: 10% vs.
13% NS
Intubation: 22.5% vs. 30% NS
Not statedThe conclusion is wrong. Data within the paper shows no signif. difference wrt number of intubations.
Study underpowered to detect differences in MAS - occurrence of which is rare.

From: Evidence tables

Cover of Intrapartum Care
Intrapartum Care: Care of Healthy Women and Their Babies During Childbirth.
NICE Clinical Guidelines, No. 55.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2007 Sep.
Copyright © 2007, National Collaborating Centre for Women’s and Children’s Health.

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