Table 6.27Study withdrawals

Withdrawals outcomeReferenceInterventionAssessment timeOutcome/effect size
Knee osteoarthritis
Manual therapy vs sham ultrasound
Number of withdrawals1 RCT (Bennell et al. 2005), N=140Manual therapy (knee taping, mobilisation, massage) + exercise vs control (sham ultrasound)12 weeks (end of treatment) and 12 weeks post-treatment12 weeks: 18% (manual) and 3% (control)
12 weeks post-treatment: 23% (manual) and 6% (control)
Control better
Number of withdrawals1 RCT (Deyle et al. 2000), N=83Manual therapy (movements, mobilisation and stretching) + exercise vs control (sham ultrasound)4 weeks (end of treatment)12% (manual) and 21% (control)
Manual better
Hip
Manual therapy vs exercise
Number of withdrawals + number lost to follow-up1 RCT (Hoeksma et al. 2004), N=109Manual therapy (manipulation + stretching) vs exerciseEnd of study (week 5) and 6 months (5 months post-intervention)N=15 (manual) and N=13 (exercise)
Both groups similar
Withdrawals due to AEs, increase of complaints1 RCT (Hoeksma et al. 2004), N=109Manual therapy (manipulation + stretching) vs exerciseEnd of study (week 5)N=3 (manual) and N=2 (exercise)
Both groups similar

From: 6, Non-pharmacological management of osteoarthritis

Cover of Osteoarthritis
Osteoarthritis: National Clinical Guideline for Care and Management in Adults.
NICE Clinical Guidelines, No. 59.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2008, Royal College of Physicians of London.

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